(1) Dr. Seheult discusses remdesivir for different categories of patients, and suggests that the drug is most beneficial (in terms of quicker recovery) for patients sick enough to require oxygen, but not so sick as to require mechanical ventilation or ECMOs (“heart-lung machines”). In this latter group, the virus has already done so much damage that remdesivir amounts to “closing the barn door after the horses have fled”, while mild cases will resolve on their own.
The conventional division of patients is (averaged across age groups):
- 80% self-limiting, self-resolving disease
- 15% get more severely ill
- 5% critically ill
So it would be the 15% where the drug can make most of the difference, probably by keeping patients from moving into the 5% critical group.
(2) Dr. John Campbell’s video looks at the asymptomatic infection rate, which he frustratingly places “between 5% and 80%”, and briefly highlights different studies that arrive…
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