Lithium is a naturally occurring substance so it is not possible to patent it. In consequence, there is no way of recovering any investments in working out how to handle its sometimes toxic side effects.
The first patients treated with lithium in 1949 were well within 2 weeks. Their discharge from the asylum where they had been living for years was delayed for a couple of months just to make sure that the medicine lithium was actually working. It was such a stunning success that their doctors had to check. The inability to patented lithium delayed its commercial availability by over two decades.
From Wikipedia at https://en.wikipedia.org/wiki/John_Cade
Boston Mayor Curley had the rare distinction of winning his first election from prison and his last while under federal indictment for corruption which he was soon convicted of while in office.
Curley won his first election in 1904 as an alderman on the slogan “he did it for a friend”. He sat a civil service exam for a friend to get him a job. He quickly then handed out 700 patronage jobs once he once he got out of prison to serve as an alderman.
In 1945, he was re-elected mayor. Truman commuted his 6 to 18 month sentence after 5 months in 1948 at the behest of the Massachusetts congressional delegation and later (1950) granted him a full pardon.
Curley was then defeated by the acting mayor during his prison term in the subsequent Democratic party primary in part because of the high taxes under the Curley regime. Naturally, during his lame-duck period, Curley granted many tax abatements to sabotage the public finances of his successor.
Second movie this week on it is heroic (Darkest Hour), treasonous (The Post) to fight on in a war you can’t win against murderously evil monsters in the hope something might turn up.