RT polio vaccine declared safe today 1955

In 1954, over 300,000 doctors, nurses, schoolteachers and other volunteers across the United States, Canada and Finland took part in one of the most complex and monumental medical trials in history.

The plan was to test the effectiveness of a newly-developed vaccine for a disease that was devastating the lives of children across the US: polio.

It was a mammoth task – a double-blind experiment, in which 650,000 schoolchildren were given the vaccine, 750,000 were given a placebo, and over 400,000 children acted as a control group and were given neither. For taking part, each participant was given a sweet and a certificate proclaiming their role as a‘Polio Pioneer’.

The results, announced in 1955, were just as monumental: the vaccine was safe and effective. As a direct result of the development of the vaccine, polio was completely eradicated in the US by 1979.

Elvis Presley’s greatest hit (was against polio)

Let’s celebrate the 61st birthday of the polio vaccine

On February 23, 1954, the polio vaccine, developed by Jonas Salk, commenced clinical testing… before the introduction of the vaccine in the mid-50’s, regular polio outbreaks occurred everywhere, even developed countries like the USA and northern Europe.

The virus is transmitted through fecal matter, so swimming pools, improper sanitation (like washing after using the bathroom), babies diapers and other sources moved the virus.

Almost all of the transmission was through casual contact, not improper sanitation (at least since the advent of a modern sanitation system in the USA starting in the late 1920’s).

About 95% of individuals infected are asymptomatic (pdf), so they appear healthy but are shedding viruses to infect other people.

Of the 5% who are symptomatic, about 10% of them eventually progress to the paralytic version of the disease. In other words, approximately 0.5% of those infected were paralyzed. One of the tropes of the anti-science/anti-vaccine world is that this is a small number. Except it isn’t. Out of 5 million children who might be infected every, approximately 25,000 children a year might progress to the paralytic version of the disease, and some of them would die.

via via Let’s celebrate the birthday of the polio vaccine.

You don’t know how lucky you are: polio was a common childhood risk in the mid-20th century – not all that long before I was born

Book Cover:  I Can Jump Puddles: Australian Children's ClassicsWhen I was in high school, we read I Can Jump Puddles (1955 ) –  an autobiography by Alan Marshall. He contracted polio in 1908 at the age of 6. At the time, I didn’t really notice how recent the threat of polio was.

Citizens of urban areas were to be terrified every summer when this frightful visitor returned.

Soon after Dr Jonas Salk’s vaccine was licensed in 1955, children’s vaccination campaigns were launched. In the U.S, following a mass immunization campaign promoted by the March of Dimes, the annual number of polio cases fell from 35,000 in 1953 to 5,600 by 1957. By 1961 only 161 cases were recorded in the United States.

File:Salk headlines.jpg

Until the Salk vaccine was introduced, polio was considered one of the most frightening public health problems in the world:

Jonas Salk made scientists and journalists alike go goofy.

As one of the only living scientists whose face was known the world over, Salk, in the public’s eye, had a superstar aura.

Airplane pilots would announce that he was on board and passengers would burst into applause. Hotels routinely would upgrade him into their penthouse suites.

A meal at a restaurant inevitably meant an interruption from an admirer, and scientists approached him with drop-jawed wonder as though some of the stardust might rub off

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